Previous research has shown that there are thousands of small molecules, the peptides, in the urine of women with ovarian cancer
A promising new method could detect early ovarian cancer from urine samples, university researchers have developed Virginia Commonwealth University.
The research was presented at the 68th Annual Meeting of the Biophysical Society, in Philadelphia, Pennsylvania.
Previous research had shown that there are thousands of small molecules, the peptidesin the urine of women with ovarian cancer.
The researcher, Josef Reiner and his colleagues sought a method to more easily detect these peptides. They turned to nanopore technology, which has the ability to simultaneously detect multiple peptides. The basic idea behind this detection involves passing molecules through a tiny pore, a nanopore, and measuring the changes that occur as the molecules move through it.
In their study, they identified and analyzed 13 peptides, including those derived from LRG-1, a biomarker found in the urine of ovarian cancer patients. Their ultimate goal is to develop a test that, when combined with other information such as transvaginal ultrasound, family history and blood tests, could improve the accuracy of detecting early-stage ovarian cancer in the future.
Source :Skai
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