Increased rates of infections upper respiratory tract in children the period of exacerbation of the Omicron strain of the SARS-CoV-2 viruswere described in a study published in the prestigious journal JAMA Pediatrics.
The Omicron mutation appears to cause less severe disease in relation to the Delta, mainly because the Omicron strain more difficult to multiply in the pulmonary parenchyma than in the upper respiratory tract.
The results of the study are summarized by the doctors of the Therapeutic Clinic of the Medical School of the National and Kapodistrian University of Athens Theodora Psaltopoulou, Panos Malandrakis, Giannis Danasis and Thanos Dimopoulos (Rector of EKPA).
Between 18,849 children treated with COVID-19 in the US, 2% had only upper respiratory tract infection. Of the 384 children with upper respiratory tract infection, 81 had severe disease (needed respiratory support, received vasoconstrictors, or ended up). The researchers compared demographic data, comorbidity and clinical outcome in children before the micron strain (March 2020-25 December 2021) and during the micron period (December 26, 2021-17 February 2022).
During the Omicron period, 178 of the 384 cases of upper respiratory infections were described (increase compared to the pre-Omicron period) and children during this period were on average younger, less likely to receive dexamethasone and less likely to develop severe disease. Children with upper respiratory disease at risk of heart failure due to the abrupt installation of the upper airway obstruction, while they may be needed treatment and in an intensive care uniteven intubation.
Although the number of cases of upper respiratory infections in children is not large, it is important to know this new pathological entity of COVID-19 and to make therapeutic decisions, say the Doctors of the Therapeutic Clinic of the Medical School of EKPA.
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