Today, thanks to gene genetics, it is possible to identify, for example, the genes that are a predisposing factor for breast cancer, then isolate them, place them in the virus and use them together with the anti-cancer virus.
The creation of personalized preventive vaccines for cancers caused by genetic factors is the ultimate goal of scientists, who are currently conducting studies to create a therapeutic vaccine that acts locally on specific forms of cancer. The head of the Department of Biotechnology and Molecular Medicine at Louisiana State University, professor of genetic engineering Konstantinos (Gus) Kousoulas, refers to the latest developments in the subject of vaccines that will act against cancer, on the occasion of his announcement that will take place tomorrow as part of the international conference NANOTECHNOLOGY 2022. Mr. Koussula’s basic research focuses on the creation of vaccines against viruses and the use of viruses to destroy cancer.
“Phase 2-3 clinical trials are currently underway in England for the herpes vaccine. In a second phase, a mutated herpes virus will be used to fight cancer. There are therapeutic vaccines with mutated herpes viruses that are being used in experimental phase 2 studies. We recently published a study that shows that the virus can be used to fight cancer with an injection that is given locally on the cancer. That is, it can be used as a local therapeutic vaccine that will eliminate carcinomas anywhere in the body. Also, until our last publication we have shown that a virus like the one we use can fight cancers and also be used in a preventive vaccine against cancer for which there is a predisposition.” points out Mr. Kousoulas.
Today, thanks to gene genetics, it is possible to identify, for example, the genes that are a predisposing factor for breast cancer, then isolate them, place them in the virus and use them together with the anti-cancer virus.
“With gene genetics, we can find out exactly which antigens are present in the body, if, for example, there is a predisposition in a certain woman for breast cancer and know that there are certain mutations in certain proteins. These genes can be isolated, placed into the virus and used along with the virus as a preventive vaccine against breast cancer. From our basic study it was shown that in mice these vaccines can be used preventively for melanomas or any other cancer. Thanks to the achievements of molecular biology we can make a general diagnosis and see in which genes there are some problems that create a certain predisposition and create a personalized vaccine for the person who has a predisposition” notes Mr. Kousoulas.
As Mr. Kousoulas points out, with the use of a special tomography that is a patent of his professor Stanford University and founder of Q Bio, Michael Snyder, the entire human body can be scanned and it can be seen how its organs work, what weaknesses exist in their function, what mutations they have, their entire genome and metabolism can be detected. Then, with the use of artificial intelligence algorithms, a combination is made that gives the exact “image” of the person and based on the resulting data, a personalized treatment can be administered.
“This CT scan can be done once a year and we can see if there are any mutations that are responsible for environmental or dietary or other factors and from there we can find out if there is a predisposition to cancer and create special vaccines that which can be administered preventively so that one does not get cancer after 20 or 30 or 40 years” adds Mr. Kousoulas.
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