Vaccination for Covid-19 during pregnancy is not linked to premature birth and low birth weight babies, according to a study released by the Centers for Disease Control and Prevention (CDC) today.
The rate of preterm birth was 4.9% among more than 10,000 women who had received at least one dose of the Covid-19 vaccine. By comparison, that figure rose to 7% among 36,000 unvaccinated women, the researchers said in their weekly report on morbidity and mortality. This difference is not considered statistically significant.
In addition, the vaccine does not increase the risk of giving birth to a baby weighing less than normal.
The results of the study support the recommendation of the CDC regarding the safety of vaccination during pregnancy.
“Evidence for the benefits of vaccination during pregnancy continues to grow, including the detection of antibodies in the umbilical cord blood,” the researchers wrote, noting that pregnant women with Covid-19 were more likely to be admitted to need mechanical respiratory support and die.
The women in the study became pregnant between May and October 2020, that is, before the vaccines became available. Almost everyone who was vaccinated did so during the second and third trimesters of pregnancy. About 96% received at least one dose of an mRNA vaccine from either Pfizer-BioNTech or Moderna. The rest did the Johnson & Johnson monosodium vaccine. No differences in results were observed depending on the time of vaccination or which vaccine was used.
Data were obtained from eight health care providers in six US states.
The researchers noted that because they studied data collected for other purposes, they may not have been aware of any vaccinations. They also did not have information on any history of complications that these women may have had in their previous pregnancies. The study did not include information on vaccinations during the first trimester of pregnancy, as well as booster doses, as they were not available at that time.
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