More than 100 passengers and crew members of the Queen Victoria cruise ship fell ill with gastrointestinal problems, CNN reports citing the US Centers for Disease Control and Prevention report.

According to the report, 139 on board – 123 passengers and 16 crew members – reported gastrointestinal symptoms including diarrhea and vomiting.

The cruise ship has isolated sick passengers and crew and is disinfecting more frequently, however the cause of the disease is not knownaccording to the CDC report.

The cruise departed from Southampton, England on January 11, then made stops in Aruba, Guatemala, Cabo San Lucas, San Francisco and Hawaii, and is expected to end on February 12, according to CNN.

They board the ship as a whole 1,824 passengers and 967 crew members.

“Cunard Cruise Line confirms that a small number of guests had reported symptoms of gastrointestinal illness on the Queen Victoria. Enhanced health and safety protocols were immediately activated to ensure the well-being of all guests and crew on board. The measures were effective,” the company said in a statement.