How blood type is related to diseases of the human body

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Blood type has been associated with individual vulnerability to various nosological entities. During the COVID-19 pandemic, data were published showing that people with blood type A were significantly more likely than people with blood type O to be infected with the SARS-CoV-2 virus, according to doctors at the Therapeutic Clinic of the School of Medicine. National and Kapodistrian University of Athens Theodora Psaltopoulou, Giannis Danasis, Panos Malandrakis and Thanos Dimopoulos (Rector of EKPA) and summarize the available preliminary data on the correlation of blood type and the occurrence of diseases in humans.

Heart disease: The risk of coronary heart disease tends to be lower for people with blood type O. Some experts argue that this may be due to the fact that people with different blood types are more likely to have elevated levels of cholesterol and a protein associated with blood clots.

Stomach and pancreatic cancer: People with blood types A, AB and B have a higher risk of developing stomach cancer and pancreatic cancer than people with blood type O. People with blood type A have a higher risk, which may be due to the fact that the infection from Helicobacter pylori is more common in people with blood type A. This bacterium is found in the stomach and intestines and can cause inflammation and ulcers.

Malaria: Malaria is transmitted by the bite of an infected mosquito that transmits the parasite to humans. The parasite then infects the human red blood cells. People with blood type C are less likely to get the parasite and develop malaria.

Peptic ulcers: Peptic ulcers are painful open sores that are more commonly found in the stomach and duodenum and are more common in people with blood type O.

Thrombosis: Deep vein thrombosis occurs when blood clots in a vein located inside the lower extremities. In this case there is a risk that the clot will move and end up in the lungs (pulmonary embolism). There is evidence that people with blood type A, B or AB have a higher risk of deep vein thrombosis.

Diabetes: The diagnosis of type 2 diabetes seems to be more common in people with blood types A and B. However, further research is needed to clarify the pathophysiological background.

Stroke: People with AB blood type have a higher risk of having a stroke, which may be due to a higher chance of developing a blood clot.

Memory: A small study showed that people with memory problems were more likely to have AB blood type, without a clear explanation as to why this happens.

‘Anxiety: Anxiety (stress) leads to an increase in cortisol levels in the blood, which is why cortisone is characterized as the stress hormone. People with blood type A tend to produce more cortisol.

Life expectancy: People with blood type C are likely to have a longer life expectancy, which may be due to the lower risk of cardiovascular disease throughout life.

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