The three doses of either the same vaccine or a combination of different vaccines “work” almost equally well in preventing Covid-19 infections, which are even caused by different variants of the coronavirus, confirms a new Chinese scientific studythe largest of its kind to date.
The findings show that the “key” to improving protection is the number of doses regardless of which combination of vaccines is given. The study (systematic review and meta-analysis) concluded that three doses – regardless of whether all three will be from the same vaccine or the third from a different one – would be sufficient to increase immunity in all age groups (and those over 65 years), in relation to the two doses.
THE third dose is particularly necessary for protection against Omicron. Also in patients with immunosuppression the third dose of mRNA vaccine improves their protection.
Researchers at the University of Hong Kong, led by Assistant Professor Peter Pak-Hong Cheung, who published the study in the British Medical Journal (BMJ), evaluated 53 studies involving more than 24 million people. different combinations of Covid-19 vaccines.
The three doses of any mRNA vaccine were found to be the most effective (96%) against preventing non-severe Covid-19 and avoiding hospitalization (95%). The third dose of mRNA vaccine after two doses of non-mRNA vaccines (eg AstraZeneca) provides satisfactory efficacy of 88%.
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