Stefanos Nikolaidis
OR paracetamol – internationally known and as acetaminophen – is one of the Most often used drugs at pregnancy. Used by millions of women worldwide, as it is considered secure solution to deal with pain and fever. However, recent statements by the US President, Donald Trumpthat the drug is associated with the autismcaused strong reactions to the scientific community.
OR international literature has indeed recorded some associations between prolonged use of paracetamol to pregnancy and neurodevelopmental disorders. However, the data is inconsistent and in no way document a causal relationship. In simple words: It does not prove that paracetamol causes autism.
Talking to skai.grthe Achilles GravanisProfessor of Pharmacology at the University of Crete, gives clear answers for the safety of drug and explains why the allegations of Trump is dangerous.
“Paracetamol is one of the safest drugs and is therefore used as an analgesic“, Emphasizes Mr. Gravanis. “It has no antithrombotic or anti -inflammatory action, which makes it suitable for use in pregnancy as opposed to other medicines, such as aspirin, which can cause bleeding or affect critical inflammatory procedures in the fetus“
As he states, the paracetamol passes him blood -brainfor this and doctors recommend taking only occasionally and not in chronic or high doses. “It will take the woman if she has some pain 2-3 days at most. If the pain continues, it must be tested in other ways“
Risks only in chronic and high doses
According to the professor, the scientific literature shows that risk for neurodevelopmental disorders exists only when the paracetamol granted to large doses and for prolonged interval.
“If we administer a pregnant woman for a month increased doses of 2-3 grams of paracetamol, we significantly increase the likelihood of about 5 to 7%, to create a condition that will be related to childbirth with neurodevelopmental disorders“, He notes.
However, even in these cases, The factor of “paracetamol” does not work alone. Need to coexist genetic predisposition of fetal and environmental agents after childbirthsuch as diet and the living conditionsto develop such disorders.
Rare side effects
The serious side effects by paracetamol is rare. The best known is the hepatotoxicitywhen taken very large doses (above 2-3 grams a day for several days), especially in combination with alcohol. “Even with a small dose of alcohol we have noticed strong toxicity in the liver“, Explains Mr. Gravanis.
The professor is categorical. “Has nothing to do with what Trump said with reality“
And ends with a clear message to pregnant women. “The epithelium is: Don’t listen to Trump, but your gynecologist. “
Source :Skai
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