Acute myocarditis – inflammation of the myocardium – caused by the coronavirus, occurred in only about two people per 1,000 patients treated with Covid-19 (0.24%), shows a new international scientific research. In these cases of patients with myocarditis, however, Covid-19 infection is more severe and is associated with more serious complications, especially if one also has pneumonia.
Myocarditis is a rare but serious condition, which causes inflammation in the heart muscle, which can lead to a weakening of the latter and its electrical system, thus making it difficult for it to function as a blood pump. An episode of myocarditis can heal on its own, require treatment, or lead to permanent heart damage.
The researchers, led by cardiologist Enrico Amirati of Niguarda Hospital in Milan and published in the American Heart Association’s Circulation, analyzed data from nearly 57,000 Covid-19 patients in 23 European hospitals and hospitals. USA. Of these, 54 had certain or possible acute myocarditis.
The study found that:
– About 2.4 patients in 1,000 developed acute myocarditis due to coronavirus.
– Acute myocarditis occurred more frequently in hospitalized patients who did not have pneumonia (57.4%).
– Those who had both acute myocarditis due to coronavirus and pneumonia had a 15% mortality rate, compared with zero deaths in the group of patients with myocarditis but no pneumonia. Patients with pneumonia were on average older (45 years) than those without pneumonia (30 years).
– One in five with confirmed myocarditis (20.4%), most of whom also had pneumonia, needed mechanical support for their blood circulation or died in hospital.
“Although Covid-19 is a virus that primarily leads to acute respiratory disease, there is a small group of people who also have heart complications,” said Dr. Amirati. The researchers estimated that the rate of myocarditis associated with Covid-19 may range from 1.2 to 5.7 cases per 1,000 hospitalized patients worldwide.
“Our analysis shows that, although rare, hospitalized patients with acute myocarditis associated with Covid-19 infection have a much higher need for admission to an intensive care unit, up to approximately 70.5% of cases, although the median age of “These patients are much younger than expected, at 38 years old,” said researcher Marco Matra, a professor of cardiology at the Italian University of Brescia.
Myocardial infarction due to vaccine is rarer
A second international studyled by cardiologist Dr. Kolengode Ramanathan of the National University Hospital of Singapore, published in The Lancet Respiratory Medicine, confirmed that myocardial infarction (inflammation of the heart) after about 18 coronary heart disease is per million doses.
The study (meta-analysis), which evaluated data from 11 studies of a total of approximately 400 million doses of Covid-19 vaccine worldwide, found that the risk of myocardial infarction after coronavirus vaccination was comparable to or lower than risk following other non-Covid-19 vaccines, associated with approximately 56 cases of myopericarditis per million doses (in the case of smallpox 132 cases / million doses).
Compared to the general population, those vaccinated against Covid-19 under 30 years of age (almost 41 cases per million doses) have a higher risk of myopicarditis than the elderly, men (23 cases per million doses) than women , those who have been vaccinated with mRNA (22.6 cases per million doses) compared to non-mRNA vaccines (8 cases), and those who have received two doses of vaccine (31 cases), as the risk of myopicarditis is higher after the second dose than after the first or third.
The study also found, analyzing data from 2.5 million Covid-19 patients, that a much higher proportion (1.1%) had myopicarditis. The researchers said that following the new data, it was clear that the benefits of the vaccine far outweighed the risks of myopicarditis.
“Myocardial infarction is a side effect of the inflammatory process caused by any vaccine and is not unique to the SARS-CoV-2 coronavirus vaccine,” said infectious disease specialist Giotti Somani, an assistant professor at the National School of Medicine.
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